A young mother and her infant child are ruthlessly gunned down while returning to their car in the garage of a shopping mall. There are no witnesses, and Detective Lindsay Boxer is left with only one shred of evidence: a cryptic message scrawled across the windshield in bloodred lipstick. The same night, the wife of A-list actor Marcus Dowling is woken by a cat burglar who is about to steal millions of dollars' worth of precious jewels. In just seconds there is a nearly empty safe, a lifeless body, and another mystery that throws San Francisco into hysteria. Lindsay spends every waking hour working with her partner, Rich -- and her desire for him threatens to tear apart both her engagement and the Women's Murder Club. Before Lindsay and her friends can piece together either case, one of the killers forces Lindsay to put her own life on the line -- but is it enough to save the city?